Propylthiouracil, Perchlorate, and Thyroid-Stimulating Hormone Modulate High Concentrations of Iodide Instigated Mitochondrial Superoxide Production in the Thyroids of Metallothionein I/II Knockout Mice

BACKGROUND: Increased oxidative stress has been suggested as one of the underlying mechanisms in iodide excess-induced thyroid disease. Metallothioneins (MTs) are regarded as scavengers of reactive oxygen species (ROS) in oxidative stress. Our aim is to investigate the effects of propylthiouracil (P...

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Detalles Bibliográficos
Autores principales: Duan, Qi, Wang, Tingting, Zhang, Na, Perera, Vern, Liang, Xue, Abeysekera, Iruni Roshanie, Yao, Xiaomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Endocrine Society 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803556/
https://www.ncbi.nlm.nih.gov/pubmed/26754589
http://dx.doi.org/10.3803/EnM.2016.31.1.174

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