Cargando…

DUP1 peptide modified micelle efficiently targeted delivery paclitaxel and enhance mitochondrial apoptosis on PSMA-negative prostate cancer cells

Prostate tumor cell targeted peptide fragment conjugated to the nano drug delivery system is a promising strategy for prostate cancer therapy. In this work, an amphiphilic copolymer Chol–PEG–DUP1 (PEG–cholesterol conjugated with DUP1 peptide) has been synthesized and characterized by proton nuclear...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Haining, Wu, Fengbo, Li, Jing, Jiang, Xuehua, Cai, Lulu, Li, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803710/
https://www.ncbi.nlm.nih.gov/pubmed/27066372
http://dx.doi.org/10.1186/s40064-016-1992-0