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Highly sensitive, non-invasive detection of colorectal cancer mutations using single molecule, third generation sequencing

Colorectal cancer (CRC) represents one of the most prevalent and lethal malignant neoplasms and every individual of age 50 and above should undergo regular CRC screening. Currently, the most effective preventive screening procedure to detect adenomatous polyps, the precursors to CRC, is colonoscopy....

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Detalles Bibliográficos
Autores principales: Russo, Giancarlo, Patrignani, Andrea, Poveda, Lucy, Hoehn, Frederic, Scholtka, Bettina, Schlapbach, Ralph, Garvin, Alex M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803778/
https://www.ncbi.nlm.nih.gov/pubmed/27054083
http://dx.doi.org/10.1016/j.atg.2015.08.006