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Possible involvement of membrane lipids peroxidation and oxidation of catalytically essential thiols of the cerebral transmembrane sodium pump as component mechanisms of iron-mediated oxidative stress-linked dysfunction of the pump's activity

The precise molecular events defining the complex role of oxidative stress in the inactivation of the cerebral sodium pump in radical-induced neurodegenerative diseases is yet to be fully clarified and thus still open. Herein we investigated the modulation of the activity of the cerebral transmembra...

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Detalles Bibliográficos
Autores principales: Omotayo, T.I., Akinyemi, G.S., Omololu, P.A., Ajayi, B.O., Akindahunsi, A.A., Rocha, J.B.T., Kade, I.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803792/
https://www.ncbi.nlm.nih.gov/pubmed/25618580
http://dx.doi.org/10.1016/j.redox.2014.12.015