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Possible involvement of membrane lipids peroxidation and oxidation of catalytically essential thiols of the cerebral transmembrane sodium pump as component mechanisms of iron-mediated oxidative stress-linked dysfunction of the pump's activity
The precise molecular events defining the complex role of oxidative stress in the inactivation of the cerebral sodium pump in radical-induced neurodegenerative diseases is yet to be fully clarified and thus still open. Herein we investigated the modulation of the activity of the cerebral transmembra...
Autores principales: | Omotayo, T.I., Akinyemi, G.S., Omololu, P.A., Ajayi, B.O., Akindahunsi, A.A., Rocha, J.B.T., Kade, I.J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803792/ https://www.ncbi.nlm.nih.gov/pubmed/25618580 http://dx.doi.org/10.1016/j.redox.2014.12.015 |
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