Valproic acid suppresses collagen by selective regulation of Smads in conjunctival fibrosis

ABSTRACT: Overproduction of type I collagen is associated with a wide range of fibrotic diseases as well as surgical failure such as in glaucoma filtration surgery (GFS). Its modulation is therefore of clinical importance. Valproic acid (VPA) is known to reduce collagen in a variety of tissues with...

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Detalles Bibliográficos
Autores principales: Seet, Li-Fong, Toh, Li Zhen, Finger, Sharon N., Chu, Stephanie W. L., Stefanovic, Branko, Wong, Tina T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803820/
https://www.ncbi.nlm.nih.gov/pubmed/26507880
http://dx.doi.org/10.1007/s00109-015-1358-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803820/
https://www.ncbi.nlm.nih.gov/pubmed/26507880
http://dx.doi.org/10.1007/s00109-015-1358-z

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