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Valproic acid suppresses collagen by selective regulation of Smads in conjunctival fibrosis
ABSTRACT: Overproduction of type I collagen is associated with a wide range of fibrotic diseases as well as surgical failure such as in glaucoma filtration surgery (GFS). Its modulation is therefore of clinical importance. Valproic acid (VPA) is known to reduce collagen in a variety of tissues with...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803820/ https://www.ncbi.nlm.nih.gov/pubmed/26507880 http://dx.doi.org/10.1007/s00109-015-1358-z |