Cargando…

Application of Inverse Liquid Chromatography for Surface Characterization of Biomaterials

In the present study, a novel approach for surface characterization of ceramic biomaterials is proposed. Two ceramic biomaterials—hydroxyapatite and β-tricalcium phosphate—were examined by means of inverse liquid chromatography. The Abraham LFER model was applied for physicochemical characteristics...

Descripción completa

Detalles Bibliográficos
Autores principales: Adamska, Katarzyna, Kadlec, Karol, Voelkel, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803825/
https://www.ncbi.nlm.nih.gov/pubmed/27069275
http://dx.doi.org/10.1007/s10337-016-3049-5
Descripción
Sumario:In the present study, a novel approach for surface characterization of ceramic biomaterials is proposed. Two ceramic biomaterials—hydroxyapatite and β-tricalcium phosphate—were examined by means of inverse liquid chromatography. The Abraham LFER model was applied for physicochemical characteristics of the surface. Different compounds, characterized by different polarity and different donor–acceptor properties of functional group, were used as test solutes. The chromatographic experiments were carried out with two compositions of the mobile phase: pure acetonitrile (MeCN) and the mixture of acetonitrile and water in 80:20 ratio (MeCN/H(2)O). Thus, the influence of mobile phase on sorption properties of hydroxyapatite and tricalcium phosphate surface was also discussed.