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Amyloid formation of growth hormone in presence of zinc: Relevance to its storage in secretory granules
Amyloids are cross-β-sheet fibrillar aggregates, associated with various human diseases and native functions such as protein/peptide hormone storage inside secretory granules of neuroendocrine cells. In the current study, using amyloid detecting agents, we show that growth hormone (GH) could be stor...
Autores principales: | Jacob, Reeba S., Das, Subhadeep, Ghosh, Saikat, Anoop, Arunagiri, Jha, Narendra Nath, Khan, Tuhin, Singru, Praful, Kumar, Ashutosh, Maji, Samir K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804206/ https://www.ncbi.nlm.nih.gov/pubmed/27004850 http://dx.doi.org/10.1038/srep23370 |
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