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Metabolic flux profiling of MDCK cells during growth and canine adenovirus vector production

Canine adenovirus vector type 2 (CAV2) represents an alternative to human adenovirus vectors for certain gene therapy applications, particularly neurodegenerative diseases. However, more efficient production processes, assisted by a greater understanding of the effect of infection on producer cells,...

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Detalles Bibliográficos
Autores principales: Carinhas, Nuno, Pais, Daniel A. M., Koshkin, Alexey, Fernandes, Paulo, Coroadinha, Ana S., Carrondo, Manuel J. T., Alves, Paula M., Teixeira, Ana P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804208/
https://www.ncbi.nlm.nih.gov/pubmed/27004747
http://dx.doi.org/10.1038/srep23529