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Metabolic flux profiling of MDCK cells during growth and canine adenovirus vector production
Canine adenovirus vector type 2 (CAV2) represents an alternative to human adenovirus vectors for certain gene therapy applications, particularly neurodegenerative diseases. However, more efficient production processes, assisted by a greater understanding of the effect of infection on producer cells,...
Autores principales: | Carinhas, Nuno, Pais, Daniel A. M., Koshkin, Alexey, Fernandes, Paulo, Coroadinha, Ana S., Carrondo, Manuel J. T., Alves, Paula M., Teixeira, Ana P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804208/ https://www.ncbi.nlm.nih.gov/pubmed/27004747 http://dx.doi.org/10.1038/srep23529 |
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