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Human EAG channels are directly modulated by PIP(2) as revealed by electrophysiological and optical interference investigations

Voltage-gated ether à go-go (EAG) K(+) channels are expressed in various types of cancer cells and also in the central nervous system. Aberrant overactivation of human EAG1 (hEAG1) channels is associated with cancer and neuronal disorders such as Zimmermann-Laband and Temple-Baraitser syndromes. Alt...

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Detalles Bibliográficos
Autores principales:	Han, Bo, He, Kunyan, Cai, Chunlin, Tang, Yin, Yang, Linli, Heinemann, Stefan H., Hoshi, Toshinori, Hou, Shangwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804213/ https://www.ncbi.nlm.nih.gov/pubmed/27005320 http://dx.doi.org/10.1038/srep23417

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