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New Findings in eNOS gene and Thalidomide Embryopathy Suggest pre-transcriptional effect variants as susceptibility factors
Antiangiogenic properties of thalidomide have created an interest in the use of the drug in treatment of cancer. However, thalidomide is responsible for thalidomide embryopathy (TE). A lack of knowledge regarding the mechanisms of thalidomide teratogenesis acts as a barrier in the aim to synthesize...
Autores principales: | Kowalski, Thayne Woycinck, Fraga, Lucas Rosa, Tovo-Rodrigues, Luciana, Sanseverino, Maria Teresa Vieira, Hutz, Mara Helena, Schuler-Faccini, Lavínia, Vianna, Fernanda Sales Luiz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804217/ https://www.ncbi.nlm.nih.gov/pubmed/27004986 http://dx.doi.org/10.1038/srep23404 |
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