Prohibitin-induced, obesity-associated insulin resistance and accompanying low-grade inflammation causes NASH and HCC

Obesity increases the risk for nonalcoholic steatohepatitis (NASH) and hepatocarcinogenesis. However, the underlying mechanisms involved in the disease process remain unclear. Recently, we have developed a transgenic obese mouse model (Mito-Ob) by prohibitin mediated mitochondrial remodeling in adip...

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Detalles Bibliográficos
Autores principales: Ande, Sudharsana R., Nguyen, K. Hoa, Grégoire Nyomba, B. L., Mishra, Suresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804274/
https://www.ncbi.nlm.nih.gov/pubmed/27005704
http://dx.doi.org/10.1038/srep23608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804274/
https://www.ncbi.nlm.nih.gov/pubmed/27005704
http://dx.doi.org/10.1038/srep23608

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