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Biallelic editing of a lamprey genome using the CRISPR/Cas9 system
Lampreys are extant representatives of agnathans. Descriptions of lamprey development, physiology and genome have provided critical insights into early evolution of vertebrate traits. However, efficient means for genetic manipulation in agnathan species have not been developed, hindering functional...
Autores principales: | Zu, Yao, Zhang, Xushuai, Ren, Jianfeng, Dong, Xuehong, Zhu, Zhe, Jia, Liang, Zhang, Qinghua, Li, Weiming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804306/ https://www.ncbi.nlm.nih.gov/pubmed/27005311 http://dx.doi.org/10.1038/srep23496 |
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