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Comparative effects of immediate‐release and extended‐release aspirin on basal and bradykinin‐stimulated excretion of thromboxane and prostacyclin metabolites

A goal of aspirin therapy is to inhibit thromboxane production and platelet aggregation without inhibiting endothelial production of the vasodilator and anti‐thrombotic prostacyclin. This study tested the hypothesis that extended‐release aspirin (NHP‐554C) would have increased selectivity for inhibi...

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Detalles Bibliográficos
Autores principales: Gamboa, Jorge L., Devin, Jessica K., Ramirez, Claudia E., Yu, Chang, Nian, Hui, Lee, Rhonda H., Brown, Nancy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804312/
https://www.ncbi.nlm.nih.gov/pubmed/27069632
http://dx.doi.org/10.1002/prp2.221

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