Nonclinical analysis of the safety, pharmacodynamics, and pharmacokinetics of plasma‐derived human FXIII concentrate in animals

Factor XIII (FXIII) is a coagulation protein which plays a major role in hemostasis by covalently cross‐linking fibrin molecules, thereby stabilizing the blood clot and increasing resistance to fibrinolysis. FXIII deficiency, either congenital or acquired, is associated with spontaneous bleeding, in...

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Detalles Bibliográficos
Autores principales: Beyerle, Andrea, Solomon, Cristina, Dickneite, Gerhard, Herzog, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804322/
https://www.ncbi.nlm.nih.gov/pubmed/27069637
http://dx.doi.org/10.1002/prp2.227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804322/
https://www.ncbi.nlm.nih.gov/pubmed/27069637
http://dx.doi.org/10.1002/prp2.227

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