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Preclinical animal anxiety research – flaws and prejudices

The current tests of anxiety in mice and rats used in preclinical research include the elevated plus‐maze (EPM) or zero‐maze (EZM), the light/dark box (LDB), and the open‐field (OF). They are currently very popular, and despite their poor achievements, they continue to exert considerable constraints...

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Detalles Bibliográficos
Autores principales: Ennaceur, Abdelkader, Chazot, Paul L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804324/
https://www.ncbi.nlm.nih.gov/pubmed/27069634
http://dx.doi.org/10.1002/prp2.223