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Biochemical and functional characterization of glycosylation-associated mutational landscapes in colon cancer
The molecular basis of aberrant protein glycosylation, a pathological alteration widespread in colorectal cancers (CRC), and the mechanisms by which it contributes to tumor progression remain largely unknown. We performed targeted re-sequencing of 430 glycosylation-associated genes in a series of pa...
Autores principales: | Venkitachalam, Srividya, Revoredo, Leslie, Varadan, Vinay, Fecteau, Ryan E., Ravi, Lakshmeswari, Lutterbaugh, James, Markowitz, Sanford D., Willis, Joseph E., Gerken, Thomas A., Guda, Kishore |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804330/ https://www.ncbi.nlm.nih.gov/pubmed/27004849 http://dx.doi.org/10.1038/srep23642 |
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