Association between insulin receptor substrate-1 polymorphisms and high platelet reactivity with clopidogrel therapy in coronary artery disease patients with type 2 diabetes mellitus

BACKGROUND: The mechanisms leading to the high on-treatment platelet reactivity in diabetes patients are not fully elucidated. The genetic factors may be associated with the diminished antiplatelet efficacy of dual antiplatelet therapy. We investigated the possible association between insulin recept...

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Detalles Bibliográficos
Autores principales: Zhang, Dingyu, Zhang, Xiaolin, Liu, Dan, Liu, Tengfei, Cai, Wenzhi, Yan, Chenghui, Han, Yaling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804508/
https://www.ncbi.nlm.nih.gov/pubmed/27005817
http://dx.doi.org/10.1186/s12933-016-0362-0

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