Cargando…

Influence of ankle fracture surgery on glycemic control in patients with diabetes

BACKGROUND: Although ankle fracture surgery can affect glycemic control by either trauma-induced stress or a postoperative decrease in physical activity, there is little evidence on this issue. This study aimed to evaluate the influence of ankle fracture surgery on glycemic control and to assess the...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Seung Yeol, Park, Moon Seok, Kwon, Soon-Sun, Sung, Ki Hyuk, Jung, Hyun Soo, Lee, Kyoung Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804547/
https://www.ncbi.nlm.nih.gov/pubmed/27005680
http://dx.doi.org/10.1186/s12891-016-0987-x
_version_ 1782423041590951936
author Lee, Seung Yeol
Park, Moon Seok
Kwon, Soon-Sun
Sung, Ki Hyuk
Jung, Hyun Soo
Lee, Kyoung Min
author_facet Lee, Seung Yeol
Park, Moon Seok
Kwon, Soon-Sun
Sung, Ki Hyuk
Jung, Hyun Soo
Lee, Kyoung Min
author_sort Lee, Seung Yeol
collection PubMed
description BACKGROUND: Although ankle fracture surgery can affect glycemic control by either trauma-induced stress or a postoperative decrease in physical activity, there is little evidence on this issue. This study aimed to evaluate the influence of ankle fracture surgery on glycemic control and to assess the risk factors for poor glycemic control after surgery in patients with diabetes. METHODS: We reviewed the medical records of consecutive patients with diabetes who underwent open reduction and internal fixation for the treatment of ankle fracture at our hospital. Patients who underwent blood testing, including fasting blood glucose (FBG), glycated hemoglobin (HbA1c), and cholesterol levels, as part of a routine check-up before surgery and again more than 2 times after surgery were included. Changes in blood test results were adjusted by multiple factors using a linear mixed model with sex, age at time of surgery, body mass index (BMI), and type of ankle fracture as the fixed effects and each subject and timing of blood test as the random effects. RESULTS: Sixty patients were ultimately included in this study. At 1 month postoperatively, mean FBG and cholesterol levels had increased significantly compared with preoperative levels (p = 0.011 and 0.024, respectively). After surgery, FBG levels showed an estimated monthly decrease of 2.2 mg/dL (p = 0.017). Sex, age at time of surgery, and type of ankle fracture did not significantly affect the monthly change in FBG level. FBG returned to the preoperative level at an estimated period of 8.1 months. BMI significantly affected preoperative FBG level (p = 0.015) but not the postoperative change in FBG level (p = 0.500). CONCLUSION: Ankle fracture surgery increased the FBG level at 1 month postoperatively. FBG levels decreased gradually after surgery at an estimated monthly rate of 2.2 mg/dL. Physicians should be aware of the difficulty in postoperative blood glucose control in patients with diabetes, even several months after surgery.
format Online
Article
Text
id pubmed-4804547
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-48045472016-03-23 Influence of ankle fracture surgery on glycemic control in patients with diabetes Lee, Seung Yeol Park, Moon Seok Kwon, Soon-Sun Sung, Ki Hyuk Jung, Hyun Soo Lee, Kyoung Min BMC Musculoskelet Disord Research Article BACKGROUND: Although ankle fracture surgery can affect glycemic control by either trauma-induced stress or a postoperative decrease in physical activity, there is little evidence on this issue. This study aimed to evaluate the influence of ankle fracture surgery on glycemic control and to assess the risk factors for poor glycemic control after surgery in patients with diabetes. METHODS: We reviewed the medical records of consecutive patients with diabetes who underwent open reduction and internal fixation for the treatment of ankle fracture at our hospital. Patients who underwent blood testing, including fasting blood glucose (FBG), glycated hemoglobin (HbA1c), and cholesterol levels, as part of a routine check-up before surgery and again more than 2 times after surgery were included. Changes in blood test results were adjusted by multiple factors using a linear mixed model with sex, age at time of surgery, body mass index (BMI), and type of ankle fracture as the fixed effects and each subject and timing of blood test as the random effects. RESULTS: Sixty patients were ultimately included in this study. At 1 month postoperatively, mean FBG and cholesterol levels had increased significantly compared with preoperative levels (p = 0.011 and 0.024, respectively). After surgery, FBG levels showed an estimated monthly decrease of 2.2 mg/dL (p = 0.017). Sex, age at time of surgery, and type of ankle fracture did not significantly affect the monthly change in FBG level. FBG returned to the preoperative level at an estimated period of 8.1 months. BMI significantly affected preoperative FBG level (p = 0.015) but not the postoperative change in FBG level (p = 0.500). CONCLUSION: Ankle fracture surgery increased the FBG level at 1 month postoperatively. FBG levels decreased gradually after surgery at an estimated monthly rate of 2.2 mg/dL. Physicians should be aware of the difficulty in postoperative blood glucose control in patients with diabetes, even several months after surgery. BioMed Central 2016-03-23 /pmc/articles/PMC4804547/ /pubmed/27005680 http://dx.doi.org/10.1186/s12891-016-0987-x Text en © Lee et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Lee, Seung Yeol
Park, Moon Seok
Kwon, Soon-Sun
Sung, Ki Hyuk
Jung, Hyun Soo
Lee, Kyoung Min
Influence of ankle fracture surgery on glycemic control in patients with diabetes
title Influence of ankle fracture surgery on glycemic control in patients with diabetes
title_full Influence of ankle fracture surgery on glycemic control in patients with diabetes
title_fullStr Influence of ankle fracture surgery on glycemic control in patients with diabetes
title_full_unstemmed Influence of ankle fracture surgery on glycemic control in patients with diabetes
title_short Influence of ankle fracture surgery on glycemic control in patients with diabetes
title_sort influence of ankle fracture surgery on glycemic control in patients with diabetes
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804547/
https://www.ncbi.nlm.nih.gov/pubmed/27005680
http://dx.doi.org/10.1186/s12891-016-0987-x
work_keys_str_mv AT leeseungyeol influenceofanklefracturesurgeryonglycemiccontrolinpatientswithdiabetes
AT parkmoonseok influenceofanklefracturesurgeryonglycemiccontrolinpatientswithdiabetes
AT kwonsoonsun influenceofanklefracturesurgeryonglycemiccontrolinpatientswithdiabetes
AT sungkihyuk influenceofanklefracturesurgeryonglycemiccontrolinpatientswithdiabetes
AT junghyunsoo influenceofanklefracturesurgeryonglycemiccontrolinpatientswithdiabetes
AT leekyoungmin influenceofanklefracturesurgeryonglycemiccontrolinpatientswithdiabetes