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Identifying the Optimal Age to Perform Newborn Screening for Hearing Loss in Uganda
BACKGROUND: Permanent congenital hearing loss affects up to 6/1000 births in developing countries. Currently, in Uganda there is no newborn screening for hearing loss (NSHL) program and no published work on this topic. Within the existing healthcare system there are two opportunities to deliver scre...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804651/ https://www.ncbi.nlm.nih.gov/pubmed/27057378 http://dx.doi.org/10.4103/2141-9248.177975 |
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author | Walsh, M Redshaw, E Crossley, E Phillips, C |
author_facet | Walsh, M Redshaw, E Crossley, E Phillips, C |
author_sort | Walsh, M |
collection | PubMed |
description | BACKGROUND: Permanent congenital hearing loss affects up to 6/1000 births in developing countries. Currently, in Uganda there is no newborn screening for hearing loss (NSHL) program and no published work on this topic. Within the existing healthcare system there are two opportunities to deliver screening, at birth or 6 weeks of age when infants receive their immunizations. AIM: This study explored the outcomes of otoacoustic emission (OAE) testing in infants at birth and 6 weeks of age, to identify the optimal age for screening. SUBJECTS AND METHODS: This cross-sectional pilot study recruited 60 consecutive infants from two health centres in Kampala, Uganda. Thirty infants were newborns recruited from the postnatal ward and 30 were aged 4–8 weeks from the immunization clinic, we performed OAE testing on all infants. RESULTS: The results showed 56.7% (17/30) of newborn infants passed OAE testing compared with 90.0% (27/30) of the immunization infants, P < 0.01. Furthermore, of the 11 newborn infants aged ≥24 h of age 90.9% (10/11) passed, compared with the 19 infants <24 h of age where 37% (7/19) passed, P < 0.01. CONCLUSIONS: This study demonstrates a higher pass rate for OAE testing for infants ≥24 h of age compared to those <24 h of age. The overall lower pass rate of the newborn infants could be due to external ear debris and middle ear fluid compromising the OAE testing. These findings would support a NSHL programme in Uganda that offers screening to infants ≥24 h of age, to maximize the cost-effectiveness of the program. |
format | Online Article Text |
id | pubmed-4804651 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-48046512016-04-07 Identifying the Optimal Age to Perform Newborn Screening for Hearing Loss in Uganda Walsh, M Redshaw, E Crossley, E Phillips, C Ann Med Health Sci Res Original Article BACKGROUND: Permanent congenital hearing loss affects up to 6/1000 births in developing countries. Currently, in Uganda there is no newborn screening for hearing loss (NSHL) program and no published work on this topic. Within the existing healthcare system there are two opportunities to deliver screening, at birth or 6 weeks of age when infants receive their immunizations. AIM: This study explored the outcomes of otoacoustic emission (OAE) testing in infants at birth and 6 weeks of age, to identify the optimal age for screening. SUBJECTS AND METHODS: This cross-sectional pilot study recruited 60 consecutive infants from two health centres in Kampala, Uganda. Thirty infants were newborns recruited from the postnatal ward and 30 were aged 4–8 weeks from the immunization clinic, we performed OAE testing on all infants. RESULTS: The results showed 56.7% (17/30) of newborn infants passed OAE testing compared with 90.0% (27/30) of the immunization infants, P < 0.01. Furthermore, of the 11 newborn infants aged ≥24 h of age 90.9% (10/11) passed, compared with the 19 infants <24 h of age where 37% (7/19) passed, P < 0.01. CONCLUSIONS: This study demonstrates a higher pass rate for OAE testing for infants ≥24 h of age compared to those <24 h of age. The overall lower pass rate of the newborn infants could be due to external ear debris and middle ear fluid compromising the OAE testing. These findings would support a NSHL programme in Uganda that offers screening to infants ≥24 h of age, to maximize the cost-effectiveness of the program. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4804651/ /pubmed/27057378 http://dx.doi.org/10.4103/2141-9248.177975 Text en Copyright: © Annals of Medical and Health Sciences Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution NonCommercial ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Walsh, M Redshaw, E Crossley, E Phillips, C Identifying the Optimal Age to Perform Newborn Screening for Hearing Loss in Uganda |
title | Identifying the Optimal Age to Perform Newborn Screening for Hearing Loss in Uganda |
title_full | Identifying the Optimal Age to Perform Newborn Screening for Hearing Loss in Uganda |
title_fullStr | Identifying the Optimal Age to Perform Newborn Screening for Hearing Loss in Uganda |
title_full_unstemmed | Identifying the Optimal Age to Perform Newborn Screening for Hearing Loss in Uganda |
title_short | Identifying the Optimal Age to Perform Newborn Screening for Hearing Loss in Uganda |
title_sort | identifying the optimal age to perform newborn screening for hearing loss in uganda |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804651/ https://www.ncbi.nlm.nih.gov/pubmed/27057378 http://dx.doi.org/10.4103/2141-9248.177975 |
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