Cargando…

SENP-1 enhances hypoxia-induced proliferation of rat pulmonary artery smooth muscle cells by regulating hypoxia-inducible factor-1α

Hypoxic pulmonary vascular remodeling (HPSR) has an important role in the development of hypoxic pulmonary hypertension. HPSR is predominantly mediated by the proliferation of pulmonary artery smooth muscle cells (PASMCs). Our previous study demonstrated that hypoxia-inducible factor (HIF)-1α was ab...

Descripción completa

Detalles Bibliográficos
Autores principales: ZHOU, FANG, DAI, AIGUO, JIANG, YONGLIANG, TAN, XIAOWU, ZHANG, XIUFENG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805078/
https://www.ncbi.nlm.nih.gov/pubmed/26935971
http://dx.doi.org/10.3892/mmr.2016.4969