Can propolis and caffeic acid phenethyl ester be promising agents against cyclophosphamide toxicity?

Propolis is a mixture having hundreds of polyphenols including caffeic acid phenethyl ester (CAPE). They have been using in several medical conditions/diseases in both in vitro and in vivo experimental setup. Cyclophosphamide (CP) has been used to treat a broad of malignancies including Hodgkin’s an...

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Detalles Bibliográficos
Autores principales: Akyol, Sumeyya, Gulec, Mehmet Akif, Erdemli, Haci Kemal, Akyol, Omer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGEYA 2016
Materias:
Mini Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805141/
https://www.ncbi.nlm.nih.gov/pubmed/27069732
http://dx.doi.org/10.5455/jice.20160127024542
Descripción
Sumario:Propolis is a mixture having hundreds of polyphenols including caffeic acid phenethyl ester (CAPE). They have been using in several medical conditions/diseases in both in vitro and in vivo experimental setup. Cyclophosphamide (CP) has been used to treat a broad of malignancies including Hodgkin’s and non-Hodgkin’s lymphoma, Burkitt’s lymphoma, chronic lymphocytic leukemia, Ewing’s sarcoma, breast cancer, testicular cancer, etc. It may cause several side effects after treatment. In this mini review, the protective effects of propolis and CAPE were compared each other in terms of effectiveness against CP-induced injuries.

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