AFM Imaging Reveals Topographic Diversity of Wild Type and Z Variant Polymers of Human α(1)-Proteinase Inhibitor

α(1)-Proteinase inhibitor (antitrypsin) is a canonical example of the serpin family member that binds and inhibits serine proteases. The natural metastability of serpins is crucial to carry out structural rearrangements necessary for biological activity. However, the enhanced metastability of the mu...

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Detalles Bibliográficos
Autores principales: Gaczynska, Maria, Karpowicz, Przemyslaw, Stuart, Christine E., Norton, Malgorzata G., Teckman, Jeffrey H., Marszal, Ewa, Osmulski, Pawel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805282/
https://www.ncbi.nlm.nih.gov/pubmed/27008547
http://dx.doi.org/10.1371/journal.pone.0151902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805282/
https://www.ncbi.nlm.nih.gov/pubmed/27008547
http://dx.doi.org/10.1371/journal.pone.0151902

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