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AFM Imaging Reveals Topographic Diversity of Wild Type and Z Variant Polymers of Human α(1)-Proteinase Inhibitor
α(1)-Proteinase inhibitor (antitrypsin) is a canonical example of the serpin family member that binds and inhibits serine proteases. The natural metastability of serpins is crucial to carry out structural rearrangements necessary for biological activity. However, the enhanced metastability of the mu...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805282/ https://www.ncbi.nlm.nih.gov/pubmed/27008547 http://dx.doi.org/10.1371/journal.pone.0151902 |