ATR promotes cilia signalling: links to developmental impacts

Mutations in ATR (ataxia telangiectasia and RAD3-related) cause Seckel syndrome (ATR-SS), a microcephalic primordial dwarfism disorder. Hitherto, the clinical manifestation of ATR deficiency has been attributed to its canonical role in DNA damage response signalling following replication fork stalli...

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Detalles Bibliográficos
Autores principales: Stiff, Tom, Casar Tena, Teresa, O'Driscoll, Mark, Jeggo, Penny A., Philipp, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805311/
https://www.ncbi.nlm.nih.gov/pubmed/26908596
http://dx.doi.org/10.1093/hmg/ddw034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805311/
https://www.ncbi.nlm.nih.gov/pubmed/26908596
http://dx.doi.org/10.1093/hmg/ddw034

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