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A low absolute number of expanded transcripts is involved in myotonic dystrophy type 1 manifestation in muscle
Muscular manifestation of myotonic dystrophy type 1 (DM1), a common inheritable degenerative multisystem disorder, is mainly caused by expression of RNA from a (CTG·CAG)(n)-expanded DM1 locus. Here, we report on comparative profiling of expression of normal and expanded endogenous or transgenic tran...
Autores principales: | Gudde, Anke E. E. G., González-Barriga, Anchel, van den Broek, Walther J. A. A., Wieringa, Bé, Wansink, Derick G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805313/ https://www.ncbi.nlm.nih.gov/pubmed/26908607 http://dx.doi.org/10.1093/hmg/ddw042 |
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