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First-Step Results of Children Presenting with Bleeding Symptoms or Abnormal Coagulation Tests in an Outpatient Clinic

OBJECTIVE: Mild bleeding symptoms are commonly seen in the general population. The aim of this study was to determine the final clinical and laboratory features of children referred for a first evaluation with a suspected bleeding disorder in the pediatric outpatient clinic of İstanbul University. M...

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Autores principales: Yıldız, İsmail, Ünüvar, Ayşegül, Kamer, İbrahim, Karaman, Serap, Uysalol, Ezgi, Kılıç, Ayşe, Oğuz, Fatma, Ünüvar, Emin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805321/
https://www.ncbi.nlm.nih.gov/pubmed/26377979
http://dx.doi.org/10.4274/tjh.2013.0370
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author Yıldız, İsmail
Ünüvar, Ayşegül
Kamer, İbrahim
Karaman, Serap
Uysalol, Ezgi
Kılıç, Ayşe
Oğuz, Fatma
Ünüvar, Emin
author_facet Yıldız, İsmail
Ünüvar, Ayşegül
Kamer, İbrahim
Karaman, Serap
Uysalol, Ezgi
Kılıç, Ayşe
Oğuz, Fatma
Ünüvar, Emin
author_sort Yıldız, İsmail
collection PubMed
description OBJECTIVE: Mild bleeding symptoms are commonly seen in the general population. The aim of this study was to determine the final clinical and laboratory features of children referred for a first evaluation with a suspected bleeding disorder in the pediatric outpatient clinic of İstanbul University. MATERIALS AND METHODS: The medical records of 26,737 outpatients who were admitted to the Division of Ambulatory Pediatrics between 31 October 2011 and 31 October 2012 were evaluated retrospectively. Ninety-nine patients were initially diagnosed as having probable bleeding disorders and were followed up. The symptoms of bleeding in addition to coagulation tests were analyzed. RESULTS: Of the 99 patients, 52 (52.5%) were male and 47 were female, and the mean age of the entire study group was 9.1±4.1 years (minimum-maximum: 2-18 years). Major bleeding symptoms were epistaxis in 36 patients (36.4%), easy bruising in 32 (32.3%), and menorrhagia in 6 (6.1%). After initial tests ordered by the pediatrician, 36 of 99 patients (36.4%) were diagnosed as having bleeding disorders that included von Willebrand disease in 12 (12.1%), hemophilia A or B in 9 (9.1%), and other rare factor deficiencies in 9 (9.1%). Six patients (6.1%) were found to have combined deficiencies. Seven of 36 patients had a family history of bleeding. CONCLUSION: Among the patients referred for bleeding disorders, 36.4% were diagnosed with a bleeding disorder with the help of primary screening tests ordered in the outpatient clinic.
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spelling pubmed-48053212016-04-06 First-Step Results of Children Presenting with Bleeding Symptoms or Abnormal Coagulation Tests in an Outpatient Clinic Yıldız, İsmail Ünüvar, Ayşegül Kamer, İbrahim Karaman, Serap Uysalol, Ezgi Kılıç, Ayşe Oğuz, Fatma Ünüvar, Emin Turk J Haematol Research Article OBJECTIVE: Mild bleeding symptoms are commonly seen in the general population. The aim of this study was to determine the final clinical and laboratory features of children referred for a first evaluation with a suspected bleeding disorder in the pediatric outpatient clinic of İstanbul University. MATERIALS AND METHODS: The medical records of 26,737 outpatients who were admitted to the Division of Ambulatory Pediatrics between 31 October 2011 and 31 October 2012 were evaluated retrospectively. Ninety-nine patients were initially diagnosed as having probable bleeding disorders and were followed up. The symptoms of bleeding in addition to coagulation tests were analyzed. RESULTS: Of the 99 patients, 52 (52.5%) were male and 47 were female, and the mean age of the entire study group was 9.1±4.1 years (minimum-maximum: 2-18 years). Major bleeding symptoms were epistaxis in 36 patients (36.4%), easy bruising in 32 (32.3%), and menorrhagia in 6 (6.1%). After initial tests ordered by the pediatrician, 36 of 99 patients (36.4%) were diagnosed as having bleeding disorders that included von Willebrand disease in 12 (12.1%), hemophilia A or B in 9 (9.1%), and other rare factor deficiencies in 9 (9.1%). Six patients (6.1%) were found to have combined deficiencies. Seven of 36 patients had a family history of bleeding. CONCLUSION: Among the patients referred for bleeding disorders, 36.4% were diagnosed with a bleeding disorder with the help of primary screening tests ordered in the outpatient clinic. Galenos Publishing 2015-12 2015-12-03 /pmc/articles/PMC4805321/ /pubmed/26377979 http://dx.doi.org/10.4274/tjh.2013.0370 Text en © Turkish Journal of Hematology, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Yıldız, İsmail
Ünüvar, Ayşegül
Kamer, İbrahim
Karaman, Serap
Uysalol, Ezgi
Kılıç, Ayşe
Oğuz, Fatma
Ünüvar, Emin
First-Step Results of Children Presenting with Bleeding Symptoms or Abnormal Coagulation Tests in an Outpatient Clinic
title First-Step Results of Children Presenting with Bleeding Symptoms or Abnormal Coagulation Tests in an Outpatient Clinic
title_full First-Step Results of Children Presenting with Bleeding Symptoms or Abnormal Coagulation Tests in an Outpatient Clinic
title_fullStr First-Step Results of Children Presenting with Bleeding Symptoms or Abnormal Coagulation Tests in an Outpatient Clinic
title_full_unstemmed First-Step Results of Children Presenting with Bleeding Symptoms or Abnormal Coagulation Tests in an Outpatient Clinic
title_short First-Step Results of Children Presenting with Bleeding Symptoms or Abnormal Coagulation Tests in an Outpatient Clinic
title_sort first-step results of children presenting with bleeding symptoms or abnormal coagulation tests in an outpatient clinic
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805321/
https://www.ncbi.nlm.nih.gov/pubmed/26377979
http://dx.doi.org/10.4274/tjh.2013.0370
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