Rhodopsin targeted transcriptional silencing by DNA-binding

Transcription factors (TFs) operate by the combined activity of their DNA-binding domains (DBDs) and effector domains (EDs) enabling the coordination of gene expression on a genomic scale. Here we show that in vivo delivery of an engineered DNA-binding protein uncoupled from the repressor domain can...

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Detalles Bibliográficos
Autores principales: Botta, Salvatore, Marrocco, Elena, de Prisco, Nicola, Curion, Fabiola, Renda, Mario, Sofia, Martina, Lupo, Mariangela, Carissimo, Annamaria, Bacci, Maria Laura, Gesualdo, Carlo, Rossi, Settimio, Simonelli, Francesca, Surace, Enrico Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Human Biology and Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805542/
https://www.ncbi.nlm.nih.gov/pubmed/26974343
http://dx.doi.org/10.7554/eLife.12242

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