A novel ciprofloxacin-resistant subclade of H58 Salmonella Typhi is associated with fluoroquinolone treatment failure

The interplay between bacterial antimicrobial susceptibility, phylogenetics and patient outcome is poorly understood. During a typhoid clinical treatment trial in Nepal, we observed several treatment failures and isolated highly fluoroquinolone-resistant Salmonella Typhi (S. Typhi). Seventy-eight S....

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Detalles Bibliográficos
Autores principales: Pham Thanh, Duy, Karkey, Abhilasha, Dongol, Sabina, Ho Thi, Nhan, Thompson, Corinne N, Rabaa, Maia A, Arjyal, Amit, Holt, Kathryn E, Wong, Vanessa, Tran Vu Thieu, Nga, Voong Vinh, Phat, Ha Thanh, Tuyen, Pradhan, Ashish, Shrestha, Saroj Kumar, Gajurel, Damoder, Pickard, Derek, Parry, Christopher M, Dougan, Gordon, Wolbers, Marcel, Dolecek, Christiane, Thwaites, Guy E, Basnyat, Buddha, Baker, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Epidemiology and Global Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805543/
https://www.ncbi.nlm.nih.gov/pubmed/26974227
http://dx.doi.org/10.7554/eLife.14003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805543/
https://www.ncbi.nlm.nih.gov/pubmed/26974227
http://dx.doi.org/10.7554/eLife.14003

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