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The Ascaris suum nicotinic receptor, ACR-16, as a drug target: Four novel negative allosteric modulators from virtual screening

Soil-transmitted helminth infections in humans and livestock cause significant debility, reduced productivity and economic losses globally. There are a limited number of effective anthelmintic drugs available for treating helminths infections, and their frequent use has led to the development of res...

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Detalles Bibliográficos
Autores principales: Zheng, Fudan, Robertson, Alan P., Abongwa, Melanie, Yu, Edward W., Martin, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805779/
https://www.ncbi.nlm.nih.gov/pubmed/27054065
http://dx.doi.org/10.1016/j.ijpddr.2016.02.001