Cargando…
The Ascaris suum nicotinic receptor, ACR-16, as a drug target: Four novel negative allosteric modulators from virtual screening
Soil-transmitted helminth infections in humans and livestock cause significant debility, reduced productivity and economic losses globally. There are a limited number of effective anthelmintic drugs available for treating helminths infections, and their frequent use has led to the development of res...
Autores principales: | Zheng, Fudan, Robertson, Alan P., Abongwa, Melanie, Yu, Edward W., Martin, Richard J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805779/ https://www.ncbi.nlm.nih.gov/pubmed/27054065 http://dx.doi.org/10.1016/j.ijpddr.2016.02.001 |
Ejemplares similares
-
Pharmacological profile of Ascaris suum ACR‐16, a new homomeric nicotinic acetylcholine receptor widely distributed in Ascaris tissues
por: Abongwa, Melanie, et al.
Publicado: (2016) -
Monepantel is a non-competitive antagonist of nicotinic acetylcholine receptors from Ascaris suum and Oesophagostomum dentatum
por: Abongwa, Melanie, et al.
Publicado: (2017) -
Are Ascaris lumbricoides and Ascaris suum a single species?
por: Leles, Daniela, et al.
Publicado: (2012) -
Ascaris lumbricoides or Ascaris suum: What′s in a Name?
por: Betson, Martha, et al.
Publicado: (2016) -
Quantitative lipidomic analysis of Ascaris suum
por: Wang, Tao, et al.
Publicado: (2020)