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Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways
Amino acid hydroxylation is a post-translational modification that regulates intra- and inter-molecular protein-protein interactions. The modifications are regulated by a family of 2-oxoglutarate- (2OG) dependent enzymes and, although the biochemistry is well understood, until now only a few substra...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805855/ https://www.ncbi.nlm.nih.gov/pubmed/26972000 http://dx.doi.org/10.1016/j.celrep.2016.02.043 |