Pharmacological Bypass of Cockayne Syndrome B Function in Neuronal Differentiation

Cockayne syndrome (CS) is a severe neurodevelopmental disorder characterized by growth abnormalities, premature aging, and photosensitivity. Mutation of Cockayne syndrome B (CSB) affects neuronal gene expression and differentiation, so we attempted to bypass its function by expressing downstream tar...

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Detalles Bibliográficos
Autores principales: Wang, Yuming, Jones-Tabah, Jace, Chakravarty, Probir, Stewart, Aengus, Muotri, Alysson, Laposa, Rebecca R., Svejstrup, Jesper Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806223/
https://www.ncbi.nlm.nih.gov/pubmed/26972010
http://dx.doi.org/10.1016/j.celrep.2016.02.051

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