Serological Survey of Hantavirus in Inhabitants from Tropical and Subtropical Areas of Brazil

Brazil has reported more than 1,600 cases of hantavirus cardiopulmonary syndrome (HPS) since 1993, with a 39% rate of reported fatalities. Using a recombinant nucleocapsid protein of Araraquara virus, we performed ELISA to detect IgG antibodies against hantavirus in human sera. The aim of this study...

Descripción completa

Detalles Bibliográficos
Autores principales: Alves Morais, Felipe, Pereira, Alexandre, Santo Pietro Pereira, Aparecida, Lazaro Moreli, Marcos, Marcelo Aranha Camargo, Luís, Schiavo Nardi, Marcello, Farah Tófoli, Cristina, Araujo, Jansen, Mara Dutra, Lilia, Lopes Ometto, Tatiana, Hurtado, Renata, Carmona de Jesus Maués, Fábio, Zingano Hinke, Tiene, Jaber Mahmud, Sati, Correia Lima, Monica, Tadeu Moraes Figueiredo, Luiz, Luiz Durigon, Edison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806265/
https://www.ncbi.nlm.nih.gov/pubmed/27034670
http://dx.doi.org/10.1155/2016/8628949
_version_ 1782423206755303424
author Alves Morais, Felipe
Pereira, Alexandre
Santo Pietro Pereira, Aparecida
Lazaro Moreli, Marcos
Marcelo Aranha Camargo, Luís
Schiavo Nardi, Marcello
Farah Tófoli, Cristina
Araujo, Jansen
Mara Dutra, Lilia
Lopes Ometto, Tatiana
Hurtado, Renata
Carmona de Jesus Maués, Fábio
Zingano Hinke, Tiene
Jaber Mahmud, Sati
Correia Lima, Monica
Tadeu Moraes Figueiredo, Luiz
Luiz Durigon, Edison
author_facet Alves Morais, Felipe
Pereira, Alexandre
Santo Pietro Pereira, Aparecida
Lazaro Moreli, Marcos
Marcelo Aranha Camargo, Luís
Schiavo Nardi, Marcello
Farah Tófoli, Cristina
Araujo, Jansen
Mara Dutra, Lilia
Lopes Ometto, Tatiana
Hurtado, Renata
Carmona de Jesus Maués, Fábio
Zingano Hinke, Tiene
Jaber Mahmud, Sati
Correia Lima, Monica
Tadeu Moraes Figueiredo, Luiz
Luiz Durigon, Edison
author_sort Alves Morais, Felipe
collection PubMed
description Brazil has reported more than 1,600 cases of hantavirus cardiopulmonary syndrome (HPS) since 1993, with a 39% rate of reported fatalities. Using a recombinant nucleocapsid protein of Araraquara virus, we performed ELISA to detect IgG antibodies against hantavirus in human sera. The aim of this study was to analyze hantavirus antibody levels in inhabitants from a tropical area (Amazon region) in Rondônia state and a subtropical (Atlantic Rain Forest) region in São Paulo state, Brazil. A total of 1,310 serum samples were obtained between 2003 and 2008 and tested by IgG-ELISA, and 82 samples (6.2%), of which 62 were from the tropical area (5.8%) and 20 from the subtropical area (8.3%), tested positive. Higher levels of hantavirus antibody were observed in inhabitants of the populous subtropical areas compared with those from the tropical areas in Brazil.
format Online
Article
Text
id pubmed-4806265
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-48062652016-03-31 Serological Survey of Hantavirus in Inhabitants from Tropical and Subtropical Areas of Brazil Alves Morais, Felipe Pereira, Alexandre Santo Pietro Pereira, Aparecida Lazaro Moreli, Marcos Marcelo Aranha Camargo, Luís Schiavo Nardi, Marcello Farah Tófoli, Cristina Araujo, Jansen Mara Dutra, Lilia Lopes Ometto, Tatiana Hurtado, Renata Carmona de Jesus Maués, Fábio Zingano Hinke, Tiene Jaber Mahmud, Sati Correia Lima, Monica Tadeu Moraes Figueiredo, Luiz Luiz Durigon, Edison Adv Virol Research Article Brazil has reported more than 1,600 cases of hantavirus cardiopulmonary syndrome (HPS) since 1993, with a 39% rate of reported fatalities. Using a recombinant nucleocapsid protein of Araraquara virus, we performed ELISA to detect IgG antibodies against hantavirus in human sera. The aim of this study was to analyze hantavirus antibody levels in inhabitants from a tropical area (Amazon region) in Rondônia state and a subtropical (Atlantic Rain Forest) region in São Paulo state, Brazil. A total of 1,310 serum samples were obtained between 2003 and 2008 and tested by IgG-ELISA, and 82 samples (6.2%), of which 62 were from the tropical area (5.8%) and 20 from the subtropical area (8.3%), tested positive. Higher levels of hantavirus antibody were observed in inhabitants of the populous subtropical areas compared with those from the tropical areas in Brazil. Hindawi Publishing Corporation 2016 2016-03-10 /pmc/articles/PMC4806265/ /pubmed/27034670 http://dx.doi.org/10.1155/2016/8628949 Text en Copyright © 2016 Felipe Alves Morais et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Alves Morais, Felipe
Pereira, Alexandre
Santo Pietro Pereira, Aparecida
Lazaro Moreli, Marcos
Marcelo Aranha Camargo, Luís
Schiavo Nardi, Marcello
Farah Tófoli, Cristina
Araujo, Jansen
Mara Dutra, Lilia
Lopes Ometto, Tatiana
Hurtado, Renata
Carmona de Jesus Maués, Fábio
Zingano Hinke, Tiene
Jaber Mahmud, Sati
Correia Lima, Monica
Tadeu Moraes Figueiredo, Luiz
Luiz Durigon, Edison
Serological Survey of Hantavirus in Inhabitants from Tropical and Subtropical Areas of Brazil
title Serological Survey of Hantavirus in Inhabitants from Tropical and Subtropical Areas of Brazil
title_full Serological Survey of Hantavirus in Inhabitants from Tropical and Subtropical Areas of Brazil
title_fullStr Serological Survey of Hantavirus in Inhabitants from Tropical and Subtropical Areas of Brazil
title_full_unstemmed Serological Survey of Hantavirus in Inhabitants from Tropical and Subtropical Areas of Brazil
title_short Serological Survey of Hantavirus in Inhabitants from Tropical and Subtropical Areas of Brazil
title_sort serological survey of hantavirus in inhabitants from tropical and subtropical areas of brazil
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806265/
https://www.ncbi.nlm.nih.gov/pubmed/27034670
http://dx.doi.org/10.1155/2016/8628949
work_keys_str_mv AT alvesmoraisfelipe serologicalsurveyofhantavirusininhabitantsfromtropicalandsubtropicalareasofbrazil
AT pereiraalexandre serologicalsurveyofhantavirusininhabitantsfromtropicalandsubtropicalareasofbrazil
AT santopietropereiraaparecida serologicalsurveyofhantavirusininhabitantsfromtropicalandsubtropicalareasofbrazil
AT lazaromorelimarcos serologicalsurveyofhantavirusininhabitantsfromtropicalandsubtropicalareasofbrazil
AT marceloaranhacamargoluis serologicalsurveyofhantavirusininhabitantsfromtropicalandsubtropicalareasofbrazil
AT schiavonardimarcello serologicalsurveyofhantavirusininhabitantsfromtropicalandsubtropicalareasofbrazil
AT farahtofolicristina serologicalsurveyofhantavirusininhabitantsfromtropicalandsubtropicalareasofbrazil
AT araujojansen serologicalsurveyofhantavirusininhabitantsfromtropicalandsubtropicalareasofbrazil
AT maradutralilia serologicalsurveyofhantavirusininhabitantsfromtropicalandsubtropicalareasofbrazil
AT lopesomettotatiana serologicalsurveyofhantavirusininhabitantsfromtropicalandsubtropicalareasofbrazil
AT hurtadorenata serologicalsurveyofhantavirusininhabitantsfromtropicalandsubtropicalareasofbrazil
AT carmonadejesusmauesfabio serologicalsurveyofhantavirusininhabitantsfromtropicalandsubtropicalareasofbrazil
AT zinganohinketiene serologicalsurveyofhantavirusininhabitantsfromtropicalandsubtropicalareasofbrazil
AT jabermahmudsati serologicalsurveyofhantavirusininhabitantsfromtropicalandsubtropicalareasofbrazil
AT correialimamonica serologicalsurveyofhantavirusininhabitantsfromtropicalandsubtropicalareasofbrazil
AT tadeumoraesfigueiredoluiz serologicalsurveyofhantavirusininhabitantsfromtropicalandsubtropicalareasofbrazil
AT luizdurigonedison serologicalsurveyofhantavirusininhabitantsfromtropicalandsubtropicalareasofbrazil

Ejemplares similares