Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIα to induce mitochondrial fragmentation

Hepatitis C virus (HCV) has long been observed to take advantage of the host mitochondria to support viral replication and assembly. The HCV core protein has been implicated to fragment host mitochondria. In this report, we have discovered that the non-structural protein 5A (NS5A) plays an instructi...

Descripción completa

Detalles Bibliográficos
Autores principales: Siu, Gavin Ka Yu, Zhou, Fan, Yu, Mei Kuen, Zhang, Leiliang, Wang, Tuanlao, Liang, Yongheng, Chen, Yangchao, Chan, Hsiao Chang, Yu, Sidney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806301/
https://www.ncbi.nlm.nih.gov/pubmed/27010100
http://dx.doi.org/10.1038/srep23464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806301/
https://www.ncbi.nlm.nih.gov/pubmed/27010100
http://dx.doi.org/10.1038/srep23464

Ejemplares similares