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Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIα to induce mitochondrial fragmentation
Hepatitis C virus (HCV) has long been observed to take advantage of the host mitochondria to support viral replication and assembly. The HCV core protein has been implicated to fragment host mitochondria. In this report, we have discovered that the non-structural protein 5A (NS5A) plays an instructi...
Autores principales: | Siu, Gavin Ka Yu, Zhou, Fan, Yu, Mei Kuen, Zhang, Leiliang, Wang, Tuanlao, Liang, Yongheng, Chen, Yangchao, Chan, Hsiao Chang, Yu, Sidney |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806301/ https://www.ncbi.nlm.nih.gov/pubmed/27010100 http://dx.doi.org/10.1038/srep23464 |
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