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Kinetic Measurements Reveal Enhanced Protein-Protein Interactions at Intercellular Junctions

The binding properties of adhesion proteins are typically quantified from measurements with soluble fragments, under conditions that differ radically from the confined microenvironment of membrane bound proteins in adhesion zones. Using classical cadherin as a model adhesion protein, we tested the p...

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Detalles Bibliográficos
Autores principales: Shashikanth, Nitesh, Kisting, Meridith A., Leckband, Deborah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806357/
https://www.ncbi.nlm.nih.gov/pubmed/27009566
http://dx.doi.org/10.1038/srep23623