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Protein tyrosine phosphatase PTP-RR regulates corticosteroid sensitivity

BACKGROUND: We have recently reported that protein phosphate 2A (PP2A) inactivation resulted in increased phosphorylation of the mitogen-activated protein kinase (MAPK) c-Jun N-terminal kinase 1 (JNK1) and glucocorticoid receptors (GR) at Ser(226), thereby reducing GR nuclear translocation and causi...

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Detalles Bibliográficos
Autores principales:	Kobayashi, Yoshiki, Ito, Kazuhiro, Kanda, Akira, Tomoda, Koich, Miller-Larsson, Anna, Barnes, Peter J., Mercado, Nicolas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806463/ https://www.ncbi.nlm.nih.gov/pubmed/27013170 http://dx.doi.org/10.1186/s12931-016-0349-0

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