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AA-PMe, a novel asiatic acid derivative, induces apoptosis and suppresses proliferation, migration, and invasion of gastric cancer cells

Asiatic acid (AA; 2α,3β,23-trihydroxyurs-12-ene-28-oic acid) is widely used for medicinal purposes in many Asian countries due to its various bioactivities. A series of AA derivatives has been synthesized in attempts to improve its therapeutic potencies. Herein we investigated the anti-tumor activit...

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Detalles Bibliográficos
Autores principales: Jing, Yue, Wang, Gang, Ge, Ying, Xu, Minjie, Tang, Shuainan, Gong, Zhunan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806767/
https://www.ncbi.nlm.nih.gov/pubmed/27073325
http://dx.doi.org/10.2147/OTT.S98849