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Plakophilin-1, a Novel Wnt Signaling Regulator, Is Critical for Tooth Development and Ameloblast Differentiation

Tooth morphogenesis is initiated by reciprocal interactions between the ectoderm and neural crest-derived mesenchyme, and the Wnt signaling pathway is involved in this process. We found that Plakophilin (PKP)1, which is associated with diseases such as ectodermal dysplasia/skin fragility syndrome, w...

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Detalles Bibliográficos
Autores principales: Miyazaki, Kanako, Yoshizaki, Keigo, Arai, Chieko, Yamada, Aya, Saito, Kan, Ishikawa, Masaki, Xue, Han, Funada, Keita, Haruyama, Naoto, Yamada, Yoshihiko, Fukumoto, Satoshi, Takahashi, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806907/
https://www.ncbi.nlm.nih.gov/pubmed/27015268
http://dx.doi.org/10.1371/journal.pone.0152206