Reconciling Longitudinal Naive T-Cell and TREC Dynamics during HIV-1 Infection

Naive T cells in untreated HIV-1 infected individuals have a reduced T-cell receptor excision circle (TREC) content. Previous mathematical models have suggested that this is due to increased naive T-cell division. It remains unclear, however, how reduced naive TREC contents can be reconciled with a...

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Detalles Bibliográficos
Autores principales: Drylewicz, Julia, Vrisekoop, Nienke, Mugwagwa, Tendai, de Boer, Anne Bregje, Otto, Sigrid A., Hazenberg, Mette D., Tesselaar, Kiki, de Boer, Rob J., Borghans, José A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806918/
https://www.ncbi.nlm.nih.gov/pubmed/27010200
http://dx.doi.org/10.1371/journal.pone.0152513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806918/
https://www.ncbi.nlm.nih.gov/pubmed/27010200
http://dx.doi.org/10.1371/journal.pone.0152513

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