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Mice Lacking Endoglin in Macrophages Show an Impaired Immune Response

Endoglin is an auxiliary receptor for members of the TGF-β superfamily and plays an important role in the homeostasis of the vessel wall. Mutations in endoglin gene (ENG) or in the closely related TGF-β receptor type I ACVRL1/ALK1 are responsible for a rare dominant vascular dysplasia, the Hereditar...

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Detalles Bibliográficos
Autores principales: Ojeda-Fernández, Luisa, Recio-Poveda, Lucía, Aristorena, Mikel, Lastres, Pedro, Blanco, Francisco J., Sanz-Rodríguez, Francisco, Gallardo-Vara, Eunate, de las Casas-Engel, Mateo, Corbí, Ángel, Arthur, Helen M., Bernabeu, Carmelo, Botella, Luisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806930/
https://www.ncbi.nlm.nih.gov/pubmed/27010826
http://dx.doi.org/10.1371/journal.pgen.1005935

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