Cross-Neutralization between Human and African Bat Mumps Viruses

Recently, a new paramyxovirus closely related to human mumps virus (MuV) was detected in bats. We generated recombinant MuVs carrying either or both of the fusion and hemagglutinin-neuraminidase bat virus glycoproteins. These viruses showed replication kinetics similar to human MuV in cultured cells...

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Detalles Bibliográficos
Autores principales: Katoh, Hiroshi, Kubota, Toru, Ihara, Toshiaki, Maeda, Ken, Takeda, Makoto, Kidokoro, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2016
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806932/
https://www.ncbi.nlm.nih.gov/pubmed/26982800
http://dx.doi.org/10.3201/eid2204.151116
Descripción
Sumario:Recently, a new paramyxovirus closely related to human mumps virus (MuV) was detected in bats. We generated recombinant MuVs carrying either or both of the fusion and hemagglutinin-neuraminidase bat virus glycoproteins. These viruses showed replication kinetics similar to human MuV in cultured cells and were neutralized efficiently by serum from healthy humans.

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