Cross-Neutralization between Human and African Bat Mumps Viruses

Recently, a new paramyxovirus closely related to human mumps virus (MuV) was detected in bats. We generated recombinant MuVs carrying either or both of the fusion and hemagglutinin-neuraminidase bat virus glycoproteins. These viruses showed replication kinetics similar to human MuV in cultured cells...

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Autores principales: Katoh, Hiroshi, Kubota, Toru, Ihara, Toshiaki, Maeda, Ken, Takeda, Makoto, Kidokoro, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2016
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806932/
https://www.ncbi.nlm.nih.gov/pubmed/26982800
http://dx.doi.org/10.3201/eid2204.151116
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author Katoh, Hiroshi
Kubota, Toru
Ihara, Toshiaki
Maeda, Ken
Takeda, Makoto
Kidokoro, Minoru
author_facet Katoh, Hiroshi
Kubota, Toru
Ihara, Toshiaki
Maeda, Ken
Takeda, Makoto
Kidokoro, Minoru
author_sort Katoh, Hiroshi
collection PubMed
description Recently, a new paramyxovirus closely related to human mumps virus (MuV) was detected in bats. We generated recombinant MuVs carrying either or both of the fusion and hemagglutinin-neuraminidase bat virus glycoproteins. These viruses showed replication kinetics similar to human MuV in cultured cells and were neutralized efficiently by serum from healthy humans.
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spelling pubmed-48069322016-04-01 Cross-Neutralization between Human and African Bat Mumps Viruses Katoh, Hiroshi Kubota, Toru Ihara, Toshiaki Maeda, Ken Takeda, Makoto Kidokoro, Minoru Emerg Infect Dis Dispatch Recently, a new paramyxovirus closely related to human mumps virus (MuV) was detected in bats. We generated recombinant MuVs carrying either or both of the fusion and hemagglutinin-neuraminidase bat virus glycoproteins. These viruses showed replication kinetics similar to human MuV in cultured cells and were neutralized efficiently by serum from healthy humans. Centers for Disease Control and Prevention 2016-04 /pmc/articles/PMC4806932/ /pubmed/26982800 http://dx.doi.org/10.3201/eid2204.151116 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Katoh, Hiroshi
Kubota, Toru
Ihara, Toshiaki
Maeda, Ken
Takeda, Makoto
Kidokoro, Minoru
Cross-Neutralization between Human and African Bat Mumps Viruses
title Cross-Neutralization between Human and African Bat Mumps Viruses
title_full Cross-Neutralization between Human and African Bat Mumps Viruses
title_fullStr Cross-Neutralization between Human and African Bat Mumps Viruses
title_full_unstemmed Cross-Neutralization between Human and African Bat Mumps Viruses
title_short Cross-Neutralization between Human and African Bat Mumps Viruses
title_sort cross-neutralization between human and african bat mumps viruses
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806932/
https://www.ncbi.nlm.nih.gov/pubmed/26982800
http://dx.doi.org/10.3201/eid2204.151116
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AT takedamakoto crossneutralizationbetweenhumanandafricanbatmumpsviruses
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