Neisseria meningitidis Serogroup X in Sub-Saharan Africa

The epidemiology of meningococcal disease varies by geography and time. Whole-genome sequencing of Neisseria meningitidis serogroup X isolates from sub-Saharan Africa and Europe showed that serogroup X emergence in sub-Saharan Africa resulted from expansion of particular variants within clonal compl...

Descripción completa

Detalles Bibliográficos
Autores principales: Agnememel, Alain, Hong, Eva, Giorgini, Dario, Nuñez-Samudio, Viginia, Deghmane, Ala-Eddine, Taha, Muhamed-Kheir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2016
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806945/
https://www.ncbi.nlm.nih.gov/pubmed/26982628
http://dx.doi.org/10.3201/eid2204.150653
Descripción
Sumario:The epidemiology of meningococcal disease varies by geography and time. Whole-genome sequencing of Neisseria meningitidis serogroup X isolates from sub-Saharan Africa and Europe showed that serogroup X emergence in sub-Saharan Africa resulted from expansion of particular variants within clonal complex 181. Virulence of these isolates in experimental mouse models was high.

Ejemplares similares