Neisseria meningitidis Serogroup X in Sub-Saharan Africa

The epidemiology of meningococcal disease varies by geography and time. Whole-genome sequencing of Neisseria meningitidis serogroup X isolates from sub-Saharan Africa and Europe showed that serogroup X emergence in sub-Saharan Africa resulted from expansion of particular variants within clonal compl...

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Autores principales: Agnememel, Alain, Hong, Eva, Giorgini, Dario, Nuñez-Samudio, Viginia, Deghmane, Ala-Eddine, Taha, Muhamed-Kheir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2016
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806945/
https://www.ncbi.nlm.nih.gov/pubmed/26982628
http://dx.doi.org/10.3201/eid2204.150653
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author Agnememel, Alain
Hong, Eva
Giorgini, Dario
Nuñez-Samudio, Viginia
Deghmane, Ala-Eddine
Taha, Muhamed-Kheir
author_facet Agnememel, Alain
Hong, Eva
Giorgini, Dario
Nuñez-Samudio, Viginia
Deghmane, Ala-Eddine
Taha, Muhamed-Kheir
author_sort Agnememel, Alain
collection PubMed
description The epidemiology of meningococcal disease varies by geography and time. Whole-genome sequencing of Neisseria meningitidis serogroup X isolates from sub-Saharan Africa and Europe showed that serogroup X emergence in sub-Saharan Africa resulted from expansion of particular variants within clonal complex 181. Virulence of these isolates in experimental mouse models was high.
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spelling pubmed-48069452016-04-01 Neisseria meningitidis Serogroup X in Sub-Saharan Africa Agnememel, Alain Hong, Eva Giorgini, Dario Nuñez-Samudio, Viginia Deghmane, Ala-Eddine Taha, Muhamed-Kheir Emerg Infect Dis Dispatch The epidemiology of meningococcal disease varies by geography and time. Whole-genome sequencing of Neisseria meningitidis serogroup X isolates from sub-Saharan Africa and Europe showed that serogroup X emergence in sub-Saharan Africa resulted from expansion of particular variants within clonal complex 181. Virulence of these isolates in experimental mouse models was high. Centers for Disease Control and Prevention 2016-04 /pmc/articles/PMC4806945/ /pubmed/26982628 http://dx.doi.org/10.3201/eid2204.150653 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Agnememel, Alain
Hong, Eva
Giorgini, Dario
Nuñez-Samudio, Viginia
Deghmane, Ala-Eddine
Taha, Muhamed-Kheir
Neisseria meningitidis Serogroup X in Sub-Saharan Africa
title Neisseria meningitidis Serogroup X in Sub-Saharan Africa
title_full Neisseria meningitidis Serogroup X in Sub-Saharan Africa
title_fullStr Neisseria meningitidis Serogroup X in Sub-Saharan Africa
title_full_unstemmed Neisseria meningitidis Serogroup X in Sub-Saharan Africa
title_short Neisseria meningitidis Serogroup X in Sub-Saharan Africa
title_sort neisseria meningitidis serogroup x in sub-saharan africa
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806945/
https://www.ncbi.nlm.nih.gov/pubmed/26982628
http://dx.doi.org/10.3201/eid2204.150653
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