Genome-wide siRNA Screening at Biosafety Level 4 Reveals a Crucial Role for Fibrillarin in Henipavirus Infection

Hendra and Nipah viruses (genus Henipavirus, family Paramyxoviridae) are highly pathogenic bat-borne viruses. The need for high biocontainment when studying henipaviruses has hindered the development of therapeutics and knowledge of the viral infection cycle. We have performed a genome-wide siRNA sc...

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Detalles Bibliográficos
Autores principales: Deffrasnes, Celine, Marsh, Glenn A., Foo, Chwan Hong, Rootes, Christina L., Gould, Cathryn M., Grusovin, Julian, Monaghan, Paul, Lo, Michael K., Tompkins, S. Mark, Adams, Timothy E., Lowenthal, John W., Simpson, Kaylene J., Stewart, Cameron R., Bean, Andrew G. D., Wang, Lin-Fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806981/
https://www.ncbi.nlm.nih.gov/pubmed/27010548
http://dx.doi.org/10.1371/journal.ppat.1005478

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