A Polyethylenimine-Containing and Transferrin-Conjugated Lipid Nanoparticle System for Antisense Oligonucleotide Delivery to AML

Limited success of antisense oligonucleotides (ASO) in clinical anticancer therapy calls for more effective delivery carriers. The goal of this study was to develop a nanoparticle system for delivery of ASO G3139, which targets mRNA of antiapoptotic protein Bcl-2, to acute myeloid leukemia (AML) cel...

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Detalles Bibliográficos
Autores principales: Yuan, Yiming, Zhang, Lijing, Cao, Hua, Yang, Yi, Zheng, Yu, Yang, Xiao-juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807046/
https://www.ncbi.nlm.nih.gov/pubmed/27034925
http://dx.doi.org/10.1155/2016/1287128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807046/
https://www.ncbi.nlm.nih.gov/pubmed/27034925
http://dx.doi.org/10.1155/2016/1287128

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